In most cases, the drug is prescribed to users in periods of 12 weeks. L^%0:T'xHGi,KGyVfZ5WI6&ZU1/VqM4.ct\i2gTAtQV%[$*/tbn"xS8JU$bljsI2)bs_/FouVGwCqX';z{0REZbSX,bXWPS#Bf|il#o'y`?jv{;!bS F#vPGzD"1~5~F%mW9YlGIQVYOS~kojbdQS!>|@Ph See DrugAbuse and Dependence (9.3). Adults Exogenous Obesity Oral. %PDF-1.6 % IBM Micromedex. Mayo Clinic does not endorse companies or products. Intravenous phentolamine (Regitine, CIBA) has been suggested on pharmacologic grounds for possible acute, severe hypertension, if this complicates overdosage. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. 1558 0 obj <>/Filter/FlateDecode/ID[<7182559B062CF74D9CEE71C953F61692>]/Index[1530 62]/Info 1529 0 R/Length 121/Prev 89015/Root 1531 0 R/Size 1592/Type/XRef/W[1 2 1]>>stream Dosage form: tablet Today, Phentermine can still be obtained through the doctors prescription in the majority of countries around the world. Many patients find that if their doctor gradually lowers their dose, for example from 37.5mg per day down to 15mg per day for the last few days, they experience fewer withdrawal symptoms and are able to keep the weight off later. 458.336, Florida Statutes - Drugs to treat obesity; rules establishing guidelines; Rule 64B8-9.012, Florida Administrative Code - Standards for the Prescription of Obesity . If the doctor finds that the patient is a good candidate for Phentermine, they may prescribe a certain dose and provide specific details on dosage and lifestyle choices that should accompany the use of this medicine. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. information and will only use or disclose that information as set forth in our notice of 97-264. Instead of simply quitting the program, a patient should rather consult a healthcare provider about quitting. The dosage varies from 15mg to 37.5mg per day. Florida Statutes Definitions Index (2022), Table Tracing Session Laws to Florida Statutes (2022), Index to Special and Local Laws (1971-2022), Index to Special and Local Laws (1845-1970). Statutes, Video Broadcast Any pharmacist who dispenses by mail a controlled substance listed in Schedule II, Schedule III, or Schedule IV is exempt from the requirement to obtain suitable identification for the prescription dispensed by mail if the pharmacist has obtained the patients identification through the patients prescription benefit plan. But the rate of misuse seems to be low. Such controlled substances may be sold only upon an order form, when such an order form is required for sale by the drug abuse laws of the United States or this state, or regulations pursuant thereto. Patients must be informed that Phentermine hydrochloride is a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity, and that coadministration of Phentermine with other drugs for weight loss is not recommended [see Indications and Usage (1) and Warnings and Precautions (5.1)]. health information, we will treat all of that information as protected health It works as a psychostimulant drug that stimulates the central nervous system to release norepinephrine from the hypothalamus. 2012 Florida Statutes. Even patients who are overweight and pregnant at the same time are not allowed to use this product. The number of such prescription, as recorded in the prescription files of the pharmacy in which it is filled. This equates to a weight loss of 10-20 pounds for a 200 pound . 2021; doi:10.1007/s13679-020-00422-w. The FDA in the United States first approved the use of Amphetamine as a drug that can be used to suppress a patients appetite in 1959. Phentermine is one of the most effective prescription weight loss medications, with FDA approval since 1959. hYr ~{L(QdK4^bdsO_d;a BXO--p,!4!,WhfM/@c Use caution in prescribing Phentermine for patients with even mild hypertension (risk of increase in blood pressure). 138 0 obj <>stream If a prescription includes a numerical notation of the quantity of the controlled substance or date, but does not include the quantity or date written out in textual format, the pharmacist may dispense the controlled substance without verification by the prescriber of the quantity or date if the pharmacy previously dispensed another prescription for the person to whom the prescription was written. Skip to Navigation | Skip to Main Content | Skip to Site Map. Current Obesity Reports. A clear, concise warning that it is a crime to transfer the controlled substance to any person other than the patient for whom prescribed. It is not uncommon for patients to experience a change in their sexual interest. JC. l 4 a ( k ( N o L i s t ( z ) . In addition to its function as an appetite suppressant, Phentermine drugs also act as energy boosters. The prescription shall be retained on file by the proprietor of the pharmacy in which it is filled for a period of 2 years. The least amount feasible should be prescribed or dispensed at one time in order to minimize the possibility of overdosage. Primary Pulmonary Hypertension (PPH) a rare, frequently fatal disease of the lungs has been reported to occur in patients receiving a combination of Phentermine with fenfluramine or dexfenfluramine. (phentermine hydrochloride) orally disintegrating tablet C IV . CIV Copyright 2000- 2023 State of Florida. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Taking more than the prescribed amount of Phentermine can lead to an overdose, which means if a patient misses a dose, they should never try to make up for it by taking more than the prescribed amount at the next dose. Should a patient realize he/she has missed a dose within a reasonable timeframe after the doses timing, it is acceptable to take it once they remember it. If the prescription is for an animal, the species of animal for which the controlled substance is prescribed. A reduction in insulin or oral hypoglycemic medications in patients with diabetes mellitus may be required. Yes, you need a prescription for phentermine. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. The dose of this medicine will be different for different patients. HB 423 (by Rep. Pigman) was signed into law on April 14, 2016. By doing this, the metabolism is revved up along with an . Fatigue and depression usually follow the central stimulation. Tell patients to keep Phentermine in a safe place to prevent theft, accidental overdose, misuse or abuse. Management of acute Phentermine hydrochloride intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. Safety and effectiveness in pediatric patients have not been established. What You Should Know Before Taking Phentermine, Frequently Asked Questions About Phentermine, refer to our phentermine drug interactions data, Frequently Asked Questions about phentermine, https://www.drugs.com/ingredient/phentermine.html, http://www.rxlist.com/adipex-p-drug/patient-avoid-while-taking.htm, http://www.everydayhealth.com/drugs/phentermine, https://www.ncbi.nlm.nih.gov/pubmed/27664021, https://www.ncbi.nlm.nih.gov/pubmed/26584649, https://www.ncbi.nlm.nih.gov/pubmed/26446094, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560177/, https://www.ncbi.nlm.nih.gov/pubmed/25911503, Feeling like they are going to faint, often accompanied by chest pain, Fluttering in the patients chest, as well as pounding heartbeats. The prescription of such weight loss enhancers is not generally appropriate for children. The name of the controlled substance prescribed and the strength, quantity, and directions for use thereof. Tablets are packaged in bottles of 100 (NDC 42806-810-01); and 1000 (NDC 42806-810-10). The usual adult dose is one tablet (37.5 mg) daily, as prescribed by the physician, administered before breakfast or 1 to 2 hours after breakfast. This content does not have an English version. A prescription for a controlled substance listed in Schedule II may not be refilled. Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances. The amount of weight loss associated with the use of an anorectic drug varies from trial to trial, and the increased weight loss appears to be related in part to variables other than the drugs prescribed, such as the physician-investigator, the population treated and the diet prescribed. law states . The FDA has categorized this drug as X for pregnancy, which means it should not be used during pregnancy under any circumstances. Portions of this document last updated: Feb. 01, 2023. One should bear in mind that Phentermine is not only a drug to help reduce the baseline body weight of patients, but it also reduces a patients risk of developing certain health diseases. In order to use Phentermine, the doctor needs to prescribe the drug for a specific patient. In some cases, the use of this drug in combination with other pills may cause the effects of other drugs to increase. You may opt-out of email communications at any time by clicking on After 12 weeks, the patient needs to take a break from the product as it may lead to physical dependence. Taking too much Phentermine can be harmful to the patients body. In some cases, the doctor may prescribe Phentermine in smaller doses and advise the patient to take it up to three times in a single day. ZeS{$d!YS,|C~E;h4DJS?|{x}~ ?`2F. It is obvious that these symptoms can make the entire program useless. 97-102; s. 301, ch. The goal of the drug is to help patients lose weight and increase energy since the withdrawal symptoms of include fatigue and weight gain through an increase in appetite, the product is rendered a waste of the patients time and money. It also isn't for people who are pregnant, may become pregnant or are breastfeeding. It can help weight loss by making you less hungry. Being extremely irritable and confused, or experienced unusual behavior or thoughts. Javascript must be enabled for site search. Over 12 weeks, it can be as high as 9-10%. Drug information provided by: Merative, Micromedex. This includes prescription and nonprescription (over-the-counter) medicines, dietary supplements, herbal remedies, or medicines for appetite control, asthma, colds, cough, hay fever, and sinus problems. Florida. This does not only include prescription drugs but also: Common drugs that are known to interact with Phentermine include Dopamine, Venlafaxine, Linezolid, Ephedrine, Isoproterenol, Epinephrine, Norepinephrine and a Phenylephrine injection. Patients must be informed about the risks of use of Phentermine (including the risks discussed in Warnings and Precautions), about the symptoms of potential adverse reactions and when to contact a physician and/or take other action. In fact, one study conducted at the Duke University School of Medicine found that apart from the Phentermines ability to effectively reduce body weight, it can also help improve a patients health-related quality of life. If the prescriber is not available to verify a prescription, the pharmacist may dispense the controlled substance but may insist that the person to whom the controlled substance is dispensed provide valid photographic identification. Burguera B, et al. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Concomitant use of alcohol with phentermine may result in an adverse drug reaction. Prescribing Information - Qsymia (Phentermine and Topiramate extended . Some of the most common withdrawal symptoms include weight gain, fatigue, insomnia and a bad mood. Committee 73-331; s. 2, ch. Place the tablet on the top of your tongue right after removing it from the bottle. Publications, Help Searching <]>> Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. To provide you with the most relevant and helpful information, and understand which endstream endobj startxref The safety and efficacy of combination therapy with Phentermine and any other drug products for weight loss including prescribed drugs, over-the-counter preparations, and herbal products, or serotonergic agents such as selective serotonin reuptake inhibitors (e.g., fluoxetine, sertraline, fluvoxamine, paroxetine), have not been established. Phentermine HCl Tablets, USP 37.5 mg privacy practices. Phentermine is a popular prescription drug that is often used to treat obesity. SE, which stands for Electronic Florida Online Reporting of Controlled Sub-stances Evaluation program. One of the most important things to consider is the fact that the drug should never be accompanied by an MAO inhibitor. 1591 0 obj <>stream Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. 0000000596 00000 n xref All rights reserved. However in the presence of topiramate, Phentermine Cmax and AUC increase 13% and 42%, respectively. The full name and address of the prescribing practitioner and the practitioners federal controlled substance registry number shall be printed thereon. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. A total of 24 patients developed heart valve disease while taking this drug, which led the FDA to withdraw the product from the market in 1997. Mayo Clinic Proceedings. The bill provides important new requirements for prescribers to generate and transmit all prescriptions electronically upon licensure renewal or by July 1, 2021, whichever is earlier. OR mail to: Attn: Dispensing Physician Registration, PO Box 946, Montgomery AL 36101-0946. (1) A pharmacist, in good faith and in the course of professional practice only, may dispense controlled substances upon a written or oral prescription of a practitioner . Disclaimer: The information on this system is unverified. All trademarks are the property of their respective owners. This combination of ingredients was branded as Fen-Phen. Studies do not permit conclusions as to the relative importance of the drug and non-drug factors on weight loss. Tablets containing 37.5 mg Phentermine hydrochloride (equivalent to 30 mg Phentermine base). Patients must be instructed on how much Phentermine to take, and when and how to take it [see Dosage and Administration (2)]. include protected health information. The effective date is January 1, 2020. Typical actions of amphetamines include central nervous system stimulation and elevation of blood pressure. See Drug Abuse and Dependence (9) and Overdosage (10). Animal reproduction studies have not been conducted with Phentermine. Your email address will not be published. Mayo Clinic does not endorse companies or products. Pharmacist and practitioner. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. endstream endobj startxref 104 0 obj <> endobj startxref Since Phentermine is a drug that contains chemical compounds, it is important to know about all of the risks that are involved with its use and precautions a person should be aware of before the consumption. include protected health information. The name of the prescribing practitioner. Florida Statutes Definitions Index (2022), Table Tracing Session Laws to Florida Statutes (2022), Index to Special and Local Laws (1971-2022), Index to Special and Local Laws (1845-1970). The number of the prescription, as recorded in the prescription files of the pharmacy in which it is filled. It can help weight loss by making you less hungry. It has the chemical name of ,,-Dimethylphenethylamine hydrochloride. These lifestyle changes often include participating in regular exercise and physical activities, as well as eating a well-balanced diet that does not contain large amounts of calories or harmful substances. Why is phentermine a controlled substance? A severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia. endstream endobj 108 0 obj <>stream It helps patients lose weight by suppressing their appetite and boosting their energy levels, thus leading to a more active lifestyle and greater calorie burn. 127: VA Prescription Monitoring Program. Store at 20 to 25C (68 to 77F) [See USP Controlled Room Temperature]. This website is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 121 0 obj <>/Filter/FlateDecode/ID[<5D80FCFEE48BF540827EEA7155FB4128>]/Index[104 35]/Info 103 0 R/Length 85/Prev 180155/Root 105 0 R/Size 139/Type/XRef/W[1 2 1]>>stream A prescription for a controlled substance listed in Schedule II may be dispensed only upon a written prescription of a practitioner, except that in an emergency situation, as defined by regulation of the Department of Health, such controlled substance may be dispensed upon oral prescription but is limited to a 72-hour supply. Take the disintegrating tablet with or without food. 2007-156; s. 5, ch. The PDMP was created in the 2009 session of the Florida legislature to encourage safer prescribing of controlled substances and reduce drug abuse and diversion within the state. Generic name: Phentermine hydrochloride 0 So some health care providers might order it for longer use. Some preparations of the formula, however, have been classified as schedule II drugs. Last updated on Mar 22, 2023. It isnt prescribed on request, but rather when a healthcare provider notices it may be beneficial for a specific patient to lose weight in order to improve their overall health or to decrease the risk of certain health concerns. Use of Phentermine is contraindicated during or within 14 days following the administration of monoamine oxidase inhibitors because of the risk of hypertensive crisis. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. If the federal government fails to oversee how the money is spent, advocates worry it will be wasted. There are reports of patients who have increased the dosage of these drugs to many times than recommended. Carefully follow your doctor's instructions for a reduced-calorie diet plan and regular exercise. History.s. There shall appear on the face of the prescription or written record thereof for the controlled substance the following information: The full name and address of the person for whom, or the owner of the animal for which, the controlled substance is dispensed. Follow your doctor's dosing instructions very carefully. Find out everything you need to know about weight loss drugs in our prescription weight loss pill guide. 0000001039 00000 n The overdose symptoms include: The side effects of Phentermine can lead to several symptoms that may impair certain functions in the patients body. Ideally, patients should take it on an empty stomach. All rights reserved. Acidification of the urine increases Phentermine excretion. 2020; doi:10.4093/dmj.2020.0258. Cumulative urinary excretion of Phentermine under uncontrolled urinary pH conditions was 62% to 85%. The possible origins of the increased weight loss due to the various drug effects are not established. 458.336 Drugs to treat obesity; rules establishing guidelines.. Requirements may be altered [see Warnings and Precautions (5.9)]. Rule 4731-11-04. It depends on supplements a patient would like to take. These are all promoted as weight loss pills that assist obese individuals. It is a class IV controlled substance because of its serious side effects and addiction potential. other information we have about you. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. 0000002991 00000 n While suffering from any of these health concerns may be a cause for concern, it does not mean a patient will not be able to use Phentermine at all. Systemic exposure of Phentermine may increase up to 91%, 45%, and 22% in patients with severe, moderate, and mild renal impairment, respectively [see Dosage and Administration (2.2) and Use in Specific Populations (8.6)]. Do not keep outdated medicine or medicine no longer needed. Or it can help you feel full longer.